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KMID : 0377519810060030351
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Chung-Ang Journal of Medicine
1981 Volume.6 No. 3 p.351 ~ p.360
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Study on Development of Pancreas
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Lee Won-Bok
Kim Dong-Chang
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Abstract
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The pancreases of human embryoes and fetuses aged from 6 to 38 weeks were studied to investigate the development of the pancreatic acini and islets, the time of appearance of islet cells, and comparison between fetal and adult islets. 1. The fusion of the ventral and dorsal pancreas was encountered for the first time on the sixth week of fetal life. 2. On the twelfth week, the primitive acinar cells appeared around the terminal portion of primitive pancreatic tubules, and showed thereafter rapid growth to look like adult acinar cells. 3. The first appearance of alpha and delta cells was on the twelfth week and that of beta cell on the thirteenth. 4. The alpha and delta cells were the major types of the pancreatic islet cells during early embryogenesis and mantle islets were identified during the second trimester.
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